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Technical challenges and limitations of current mouse models of ovarian cancer

The development of genetically engineered models (GEM) of epithelial ovarian cancer (EOC) has been very successful, with well validated models representing high grade and low grade serous adenocarcinomas and endometrioid carcinoma (EC). Most of these models were developed using technologies intended...

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Detalles Bibliográficos
Autores principales: Garson, Kenneth, Gamwell, Lisa F, Pitre, Elizabeth MG, Vanderhyden, Barbara C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537528/
https://www.ncbi.nlm.nih.gov/pubmed/23190474
http://dx.doi.org/10.1186/1757-2215-5-39