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Angiogenesis in metastatic colorectal cancer and the benefits of targeted therapy
The diverse pathways and molecules involved in angiogenesis, the formation of new blood vessels, have been targeted for the treatment of colorectal and other cancers. Vascular endothelial growth factor (VEGF)-A binding to VEGF receptor (VEGFR)-2 is believed to be the key signaling pathway mediating...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537532/ https://www.ncbi.nlm.nih.gov/pubmed/23057939 http://dx.doi.org/10.1186/1756-8722-5-63 |