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Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms

BACKGROUND: The aim of this study was to investigate whether obestatin (OB), a peptide mediator encoded by the ghrelin gene exerting a protective effect in ischemic reperfused heart, is able to reduce cardiac dysfunctions in adult diabetic rats. METHODS: Diabetes was induced by STZ injection (50 mg/...

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Detalles Bibliográficos
Autores principales: Aragno, Manuela, Mastrocola, Raffaella, Ghé, Corrado, Arnoletti, Elisa, Bassino, Eleonora, Alloatti, Giuseppe, Muccioli, Giampiero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537569/
https://www.ncbi.nlm.nih.gov/pubmed/23066908
http://dx.doi.org/10.1186/1475-2840-11-129