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Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition

BACKGROUND: Lycorine, a natural alkaloid extracted from Amaryllidaceae, has shown various pharmacological effects. Recent studies have focused on the potential antitumor activity of lycorine. In our previous study, we found that lycorine decrease the cell viability of leukemia HL-60 cells and multip...

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Detalles Bibliográficos
Autores principales: Li, Lv, Dai, Hong-Juan, Ye, Mao, Wang, Shu-Ling, Xiao, Xiao-Juan, Zheng, Jie, Chen, Hui-Yong, Luo, Yu-hao, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537594/
https://www.ncbi.nlm.nih.gov/pubmed/23176676
http://dx.doi.org/10.1186/1475-2867-12-49