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The role of the C8 proton of ATP in the catalysis of shikimate kinase and adenylate kinase

BACKGROUND: It has been demonstrated that the adenyl moiety of ATP plays a direct role in the regulation of ATP binding and/or phosphoryl transfer within a range of kinase and synthetase enzymes. The role of the C8-H of ATP in the binding and/or phosphoryl transfer on the enzyme activity of a number...

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Detalles Bibliográficos
Autores principales: Kenyon, Colin P, Roth, Robyn L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537612/
https://www.ncbi.nlm.nih.gov/pubmed/22876783
http://dx.doi.org/10.1186/1471-2091-13-15