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Focal DNA Copy Number Changes in Neuroblastoma Target MYCN Regulated Genes

Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segments. A recent whole genome sequencing effort yielde...

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Detalles Bibliográficos
Autores principales: Kumps, Candy, Fieuw, Annelies, Mestdagh, Pieter, Menten, Björn, Lefever, Steve, Pattyn, Filip, De Brouwer, Sara, Sante, Tom, Schulte, Johannes Hubertus, Schramm, Alexander, Van Roy, Nadine, Van Maerken, Tom, Noguera, Rosa, Combaret, Valérie, Devalck, Christine, Westermann, Frank, Laureys, Geneviève, Eggert, Angelika, Vandesompele, Jo, De Preter, Katleen, Speleman, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537730/
https://www.ncbi.nlm.nih.gov/pubmed/23308108
http://dx.doi.org/10.1371/journal.pone.0052321