Cargando…

The origins of the evolutionary signal used to predict protein-protein interactions

BACKGROUND: The correlation of genetic distances between pairs of protein sequence alignments has been used to infer protein-protein interactions. It has been suggested that these correlations are based on the signal of co-evolution between interacting proteins. However, although mutations in differ...

Descripción completa

Detalles Bibliográficos
Autores principales: Swapna, Lakshmipuram S, Srinivasan, Narayanaswamy, Robertson, David L, Lovell, Simon C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537733/
https://www.ncbi.nlm.nih.gov/pubmed/23217198
http://dx.doi.org/10.1186/1471-2148-12-238