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The origins of the evolutionary signal used to predict protein-protein interactions
BACKGROUND: The correlation of genetic distances between pairs of protein sequence alignments has been used to infer protein-protein interactions. It has been suggested that these correlations are based on the signal of co-evolution between interacting proteins. However, although mutations in differ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537733/ https://www.ncbi.nlm.nih.gov/pubmed/23217198 http://dx.doi.org/10.1186/1471-2148-12-238 |