gp96 expression in neutrophils is critical for the onset of Escherichia coli K1 (RS218) meningitis

Despite the fundamental function of neutrophils (PMNs) in innate immunity, their role in Escherichia coli K1 (EC-K1) induced meningitis is unexplored. Here we show that PMN-depleted mice are resistant to EC-K1 (RS218) meningitis. EC-K1 survives and multiplies in PMNs for which outer membrane protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Mittal, Rahul, Prasadarao, Nemani V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537828/
https://www.ncbi.nlm.nih.gov/pubmed/22109526
http://dx.doi.org/10.1038/ncomms1554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537828/
https://www.ncbi.nlm.nih.gov/pubmed/22109526
http://dx.doi.org/10.1038/ncomms1554

Ejemplares similares