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gp96 expression in neutrophils is critical for the onset of Escherichia coli K1 (RS218) meningitis
Despite the fundamental function of neutrophils (PMNs) in innate immunity, their role in Escherichia coli K1 (EC-K1) induced meningitis is unexplored. Here we show that PMN-depleted mice are resistant to EC-K1 (RS218) meningitis. EC-K1 survives and multiplies in PMNs for which outer membrane protein...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537828/ https://www.ncbi.nlm.nih.gov/pubmed/22109526 http://dx.doi.org/10.1038/ncomms1554 |