A Complex Network of Factors with Overlapping Affinities Repress Splicing through Intronic Elements

To better understand splicing regulation, we used a cell-based screen to identify ten diverse motifs that inhibit splicing from intron. Each motif was validated in another human cell type and gene context, and their presence correlated with in vivo splicing changes. All motifs exhibited exonic splic...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Xiao, Xinshu, Zhang, Jianming, Choudhury, Rajarshi, Robertson, Alex, Li, Kai, Ma, Meng, Burge, Christopher B., Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537874/
https://www.ncbi.nlm.nih.gov/pubmed/23241926
http://dx.doi.org/10.1038/nsmb.2459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537874/
https://www.ncbi.nlm.nih.gov/pubmed/23241926
http://dx.doi.org/10.1038/nsmb.2459

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