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A Complex Network of Factors with Overlapping Affinities Repress Splicing through Intronic Elements
To better understand splicing regulation, we used a cell-based screen to identify ten diverse motifs that inhibit splicing from intron. Each motif was validated in another human cell type and gene context, and their presence correlated with in vivo splicing changes. All motifs exhibited exonic splic...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537874/ https://www.ncbi.nlm.nih.gov/pubmed/23241926 http://dx.doi.org/10.1038/nsmb.2459 |