S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells

Previous studies suggest that levels of the astrocyte-derived S100B protein, such as those occurring in brain extra-cellular spaces consequent to persistent astroglial activation, may have a pathogenetic role in Alzheimer's disease (AD). Although S100B was reported to promote β amyloid precurso...

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Detalles Bibliográficos
Autores principales: Esposito, Giuseppe, Scuderi, Caterina, Lu, Jie, Savani, Claudia, De Filippis, Daniele, Iuvone, Teresa, Steardo Jr, Luca, Sheen, Volney, Steardo, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538024/
https://www.ncbi.nlm.nih.gov/pubmed/18494933
http://dx.doi.org/10.1111/j.1582-4934.2008.00159.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538024/
https://www.ncbi.nlm.nih.gov/pubmed/18494933
http://dx.doi.org/10.1111/j.1582-4934.2008.00159.x

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