Cargando…

S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells

Previous studies suggest that levels of the astrocyte-derived S100B protein, such as those occurring in brain extra-cellular spaces consequent to persistent astroglial activation, may have a pathogenetic role in Alzheimer's disease (AD). Although S100B was reported to promote β amyloid precurso...

Descripción completa

Detalles Bibliográficos
Autores principales:	Esposito, Giuseppe, Scuderi, Caterina, Lu, Jie, Savani, Claudia, De Filippis, Daniele, Iuvone, Teresa, Steardo Jr, Luca, Sheen, Volney, Steardo, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538024/ https://www.ncbi.nlm.nih.gov/pubmed/18494933 http://dx.doi.org/10.1111/j.1582-4934.2008.00159.x

Ejemplares similares

Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide
por: Scuderi, Caterina, et al.
Publicado: (2011)

Differential Cannabinoid Receptor Expression during Reactive Gliosis: a Possible Implication for a Nonpsychotropic Neuroprotection
por: De Filippis, Daniele, et al.
Publicado: (2009)

Astrocytes and the Psychiatric Sequelae of COVID-19: What We Learned from the Pandemic
por: Steardo, Luca, et al.
Publicado: (2022)

S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors
por: Lu, Jie, et al.
Publicado: (2011)

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement
por: Esposito, Giuseppe, et al.
Publicado: (2011)

Does neuroinflammation turn on the flame in Alzheimer's disease? Focus on astrocytes
por: Steardo, Luca, et al.
Publicado: (2015)

S100B Inhibitor Pentamidine Attenuates Reactive Gliosis and Reduces Neuronal Loss in a Mouse Model of Alzheimer's Disease
por: Cirillo, Carla, et al.
Publicado: (2015)

Systemic Inflammation and Astrocyte Reactivity in the Neuropsychiatric Sequelae of COVID-19: Focus on Autism Spectrum Disorders
por: Valenza, Marta, et al.
Publicado: (2021)

Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis
por: De Filippis, Daniele, et al.
Publicado: (2011)

Altered Waste Disposal System in Aging and Alzheimer’s Disease: Focus on Astrocytic Aquaporin-4
por: Valenza, Marta, et al.
Publicado: (2020)

Palmitoylethanolamide and White Matter Lesions: Evidence for Therapeutic Implications
por: Valenza, Marta, et al.
Publicado: (2022)

Targeting neuroinflammation in Alzheimer’s disease
por: Bronzuoli, Maria Rosanna, et al.
Publicado: (2016)

Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α
por: Scuderi, Caterina, et al.
Publicado: (2012)

Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer's Disease: In Vitro and In Vivo Evidence
por: Bronzuoli, Maria Rosanna, et al.
Publicado: (2018)

Alternative Targets to Fight Alzheimer’s Disease: Focus on Astrocytes
por: Valenza, Marta, et al.
Publicado: (2021)

The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice
por: Esposito, Giuseppe, et al.
Publicado: (2012)

Psychiatric face of COVID-19
por: Steardo, Luca, et al.
Publicado: (2020)

Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling
por: Wan, Wenbin, et al.
Publicado: (2019)

Astrocyte Function Is Affected by Aging and Not Alzheimer’s Disease: A Preliminary Investigation in Hippocampi of 3xTg-AD Mice
por: Bronzuoli, Maria Rosanna, et al.
Publicado: (2019)

Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer’s disease
por: Scuderi, Caterina, et al.
Publicado: (2014)

Co-Ultramicronized Palmitoylethanolamide/Luteolin Restores Oligodendrocyte Homeostasis via Peroxisome Proliferator-Activated Receptor-α in an In Vitro Model of Alzheimer’s Disease
por: Facchinetti, Roberta, et al.
Publicado: (2022)

Hyperphosphorylation-Induced Tau Oligomers
por: Iqbal, Khalid, et al.
Publicado: (2013)

Application of Support Vector Machine on fMRI Data as Biomarkers in Schizophrenia Diagnosis: A Systematic Review
por: Steardo, Luca, et al.
Publicado: (2020)

Ultramicronized palmitoylethanolamide rescues learning and memory impairments in a triple transgenic mouse model of Alzheimer’s disease by exerting anti-inflammatory and neuroprotective effects
por: Scuderi, Caterina, et al.
Publicado: (2018)

Endocannabinoid System as Therapeutic Target of PTSD: A Systematic Review
por: Steardo, Luca, et al.
Publicado: (2021)

Looking for a Treatment for the Early Stage of Alzheimer’s Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin
por: Facchinetti, Roberta, et al.
Publicado: (2020)

Editorial: Dysmetabolism, Obesity, and Inflammation: Three Prominent Actors in the Drama of Major Neuropsychiatric Disorders
por: Cassano, Tommaso, et al.
Publicado: (2016)

Neuroglia in the autistic brain: evidence from a preclinical model
por: Bronzuoli, Maria Rosanna, et al.
Publicado: (2018)

Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau
por: Melov, Simon, et al.
Publicado: (2007)

Hyperphosphorylated tau in young and middle-aged subjects
por: Elobeid, Adila, et al.
Publicado: (2011)

PINCH in the Cellular Stress Response to Tau-Hyperphosphorylation
por: Ozdemir, Ahmet Yunus, et al.
Publicado: (2013)

Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
por: Tepper, Katharina, et al.
Publicado: (2014)

Immunological memory to hyperphosphorylated tau in asymptomatic individuals
por: Pascual, Gabriel, et al.
Publicado: (2017)

Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer’s Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated
por: Barthélemy, Nicolas R., et al.
Publicado: (2022)

Zinc Binding Directly Regulates Tau Toxicity Independent of Tau Hyperphosphorylation
por: Huang, Yunpeng, et al.
Publicado: (2014)

Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging
por: Yuan, Minghao, et al.
Publicado: (2022)

Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion
por: Plouffe, Vanessa, et al.
Publicado: (2012)

Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset
por: Rodriguez-Callejas, Juan D., et al.
Publicado: (2016)

The Efficacy of Imrecoxib and Celecoxib in Axial Spondyloarthritis and Their Influence on Serum Dickopff-Related Protein 1 (DKK-1) Levels
por: Gao, Guan-Min, et al.
Publicado: (2017)

Serum Dickopff 1 as a Novel Biomarker in Hepatocellular Carcinoma Diagnosis and Follow Up After Ablative Therapy
por: Younis, Yehia Sadek, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_f18oq519avdej6hae5d5k51r9p