Terpenic fraction of Pterodon pubescens inhibits nuclear factor kappa B and extracellular signal-regulated protein Kinase 1/2 activation and deregulates gene expression in leukemia cells

BACKGROUND: Plant derived compounds have been shown to be important sources of several anti-cancer agents. As cell cycle deregulation and tumor growth are intimately linked, the discovery of new substances targeting events in this biochemical pathway would be of great value. The anti-leukemic effect...

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Detalles Bibliográficos
Autores principales: Pereira, Monica Farah, Martino, Thiago, Dalmau, Sergio Ranto, Paes, Márcia Cristina, Barja-Fidalgo, Christina, Albano, Rodolpho Mattos, Coelho, Marsen Garcia Pinto, Sabino, Kátia Costa de Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538048/
https://www.ncbi.nlm.nih.gov/pubmed/23181557
http://dx.doi.org/10.1186/1472-6882-12-231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538048/
https://www.ncbi.nlm.nih.gov/pubmed/23181557
http://dx.doi.org/10.1186/1472-6882-12-231

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