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Terpenic fraction of Pterodon pubescens inhibits nuclear factor kappa B and extracellular signal-regulated protein Kinase 1/2 activation and deregulates gene expression in leukemia cells
BACKGROUND: Plant derived compounds have been shown to be important sources of several anti-cancer agents. As cell cycle deregulation and tumor growth are intimately linked, the discovery of new substances targeting events in this biochemical pathway would be of great value. The anti-leukemic effect...
Autores principales: | Pereira, Monica Farah, Martino, Thiago, Dalmau, Sergio Ranto, Paes, Márcia Cristina, Barja-Fidalgo, Christina, Albano, Rodolpho Mattos, Coelho, Marsen Garcia Pinto, Sabino, Kátia Costa de Carvalho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538048/ https://www.ncbi.nlm.nih.gov/pubmed/23181557 http://dx.doi.org/10.1186/1472-6882-12-231 |
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