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Pandemic influenza vaccine: characterization of A/California/07/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability

BACKGROUND: The recent H1N1 influenza pandemic illustrated the shortcomings of the vaccine manufacturing process. The A/California/07/2009 H1N1 pandemic influenza vaccine or A(H1N1)pdm09 was available late and in short supply as a result of delays in production caused by low yields and poor antigen...

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Detalles Bibliográficos
Autores principales: Feshchenko, Elena, Rhodes, David G, Felberbaum, Rachael, McPherson, Clifton, Rininger, Joseph A, Post, Penny, Cox, Manon MJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538074/
https://www.ncbi.nlm.nih.gov/pubmed/23110350
http://dx.doi.org/10.1186/1472-6750-12-77