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Use of alternative promoters may hide genetic effects on phenotypic traits

Genome-wide association studies (GWAS) have identified a multitude of single nucleotide polymorphisms (SNPs) associated with a wide spectrum of human phenotypic traits. However, the SNPs identified so far do not explain much of the expected genetic variation and they are poor predictors of the occur...

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Detalles Bibliográficos
Autor principal: Ruiz-Narváez, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538106/
https://www.ncbi.nlm.nih.gov/pubmed/23034535
http://dx.doi.org/10.1038/jhg.2012.115