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Synthesis of Cyclic Py-Im Polyamide Libraries

[Image: see text] Cyclic Py-Im polyamides containing two GABA turn units exhibit enhanced DNA binding affinity, but extensive studies of their biological properties have been hindered due to synthetic inaccessibility. A facile modular approach toward cyclic polyamides has been developed via microwav...

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Detalles Bibliográficos
Autores principales: Li, Benjamin C., Montgomery, David C., Puckett, James W., Dervan, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538502/
https://www.ncbi.nlm.nih.gov/pubmed/23106218
http://dx.doi.org/10.1021/jo302053v