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Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET

BACKGROUND: Currently, (68)Ga-labeled 1,4,7,10-tetraazacyclododecane-tetraacetic acid (DOTA)-peptides are the most widely used class of (68)Ga radiotracers for PET, although DOTA is not optimal for (68)Ga complexation. More recently, 1,4,7-triazacyclononane-triacetic acid (NOTA) and particularly tri...

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Detalles Bibliográficos
Autores principales: Notni, Johannes, Pohle, Karolin, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538506/
https://www.ncbi.nlm.nih.gov/pubmed/22682112
http://dx.doi.org/10.1186/2191-219X-2-28