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A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs

BACKGROUND: Dopamine receptor D(4)(DRD4) polymorphisms have been associated with a number of psychiatric disorders, but little is known about the mechanism of these associations. DNA methylation is linked to the regulation of gene expression and plays a vital role in normal cellular function, with a...

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Detalles Bibliográficos
Autores principales: Docherty, Sophia J, Davis, Oliver SP, Haworth, Claire MA, Plomin, Robert, D’Souza, Ursula, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538530/
https://www.ncbi.nlm.nih.gov/pubmed/22691691
http://dx.doi.org/10.1186/1744-9081-8-31