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Use of PB-Cre4 Mice for Mosaic Gene Deletion
Transgene expression from short promoters in transgenic animals can lead to unwanted transgene expression patterns, often as a byproduct of random integration of the expression cassette into the host genome. Here I demonstrate that the often used PB-Cre4 line (also referred to as “Probasin-Cre”), al...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538545/ https://www.ncbi.nlm.nih.gov/pubmed/23308238 http://dx.doi.org/10.1371/journal.pone.0053501 |