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Chronic Morphine Treatment Attenuates Cell Growth of Human BT474 Breast Cancer Cells by Rearrangement of the ErbB Signalling Network

BACKGROUND: There is increasing evidence that opioid analgesics may interfere with tumour growth. It is currently thought that these effects are mediated by transactivation of receptor tyrosine kinase (RTK)-controlled ERK1/2 and Akt signalling. The growth of many breast cancer cells is dependent on...

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Detalles Bibliográficos
Autores principales: Weingaertner, Inka Regine, Koutnik, Sarah, Ammer, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538590/
https://www.ncbi.nlm.nih.gov/pubmed/23308242
http://dx.doi.org/10.1371/journal.pone.0053510