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Functional Characterization of Domains of IPS-1 Using an Inducible Oligomerization System

The innate immune system recognizes viral nucleic acids and stimulates cellular antiviral responses. Intracellular detection of viral RNA is mediated by the Retinoic acid inducible gene (RIG)-I Like Receptor (RLR), leading to production of type I interferon (IFN) and pro-inflammatory cytokines. Once...

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Detalles Bibliográficos
Autores principales: Takamatsu, Shiori, Onoguchi, Kazuhide, Onomoto, Koji, Narita, Ryo, Takahasi, Kiyohiro, Ishidate, Fumiyoshi, Fujiwara, Takahiro K., Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538592/
https://www.ncbi.nlm.nih.gov/pubmed/23308256
http://dx.doi.org/10.1371/journal.pone.0053578