Synthesized Multiple Antigenic Polypeptide Vaccine Based on B-Cell Epitopes of Human Heparanase Could Elicit a Potent Antimetastatic Effect on Human Hepatocellular Carcinoma In Vivo

AIMS: The aim of this study was to investigate the antimetastatic effect of multiple antigenic polypeptide (MAP) vaccine based on B-cell epitopes of heparanase (HPSE) on human hepatocellular carcinoma (HCC) in vivo. METHODS: The antiserum against B-cell epitopes of HPSE was isolated, purified and ch...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Yang, Jian-min, Wang, Hui-ju, Ru, Guo-qing, Fan, Dai-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538634/
https://www.ncbi.nlm.nih.gov/pubmed/23308126
http://dx.doi.org/10.1371/journal.pone.0052940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538634/
https://www.ncbi.nlm.nih.gov/pubmed/23308126
http://dx.doi.org/10.1371/journal.pone.0052940

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