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Autophagy Plays an Essential Role in Mediating Regression of Hypertrophy during Unloading of the Heart
Autophagy is a bulk degradation mechanism for cytosolic proteins and organelles. The heart undergoes hypertrophy in response to mechanical load but hypertrophy can regress upon unloading. We hypothesize that autophagy plays an important role in mediating regression of cardiac hypertrophy during unlo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538681/ https://www.ncbi.nlm.nih.gov/pubmed/23308102 http://dx.doi.org/10.1371/journal.pone.0051632 |