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Autophagy Plays an Essential Role in Mediating Regression of Hypertrophy during Unloading of the Heart

Autophagy is a bulk degradation mechanism for cytosolic proteins and organelles. The heart undergoes hypertrophy in response to mechanical load but hypertrophy can regress upon unloading. We hypothesize that autophagy plays an important role in mediating regression of cardiac hypertrophy during unlo...

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Detalles Bibliográficos
Autores principales:	Hariharan, Nirmala, Ikeda, Yoshiyuki, Hong, Chull, Alcendor, Ralph R., Usui, Soichiro, Gao, Shumin, Maejima, Yasuhiro, Sadoshima, Junichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538681/ https://www.ncbi.nlm.nih.gov/pubmed/23308102 http://dx.doi.org/10.1371/journal.pone.0051632

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