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Load Regulates Bone Formation and Sclerostin Expression through a TGFβ-Dependent Mechanism

Bone continually adapts to meet changing physical and biological demands. Osteoblasts, osteoclasts, and osteocytes cooperate to integrate these physical and biochemical cues to maintain bone homeostasis. Although TGFβ acts on all three of these cell types to maintain bone homeostasis, the extent to...

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Detalles Bibliográficos
Autores principales: Nguyen, Jacqueline, Tang, Simon Y., Nguyen, Daniel, Alliston, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538690/
https://www.ncbi.nlm.nih.gov/pubmed/23308287
http://dx.doi.org/10.1371/journal.pone.0053813