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Load Regulates Bone Formation and Sclerostin Expression through a TGFβ-Dependent Mechanism
Bone continually adapts to meet changing physical and biological demands. Osteoblasts, osteoclasts, and osteocytes cooperate to integrate these physical and biochemical cues to maintain bone homeostasis. Although TGFβ acts on all three of these cell types to maintain bone homeostasis, the extent to...
Autores principales: | Nguyen, Jacqueline, Tang, Simon Y., Nguyen, Daniel, Alliston, Tamara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538690/ https://www.ncbi.nlm.nih.gov/pubmed/23308287 http://dx.doi.org/10.1371/journal.pone.0053813 |
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