How Does (E)-2-(Acetamidomethylene)succinate Bind to Its Hydrolase? From the Binding Process to the Final Result

The binding of (E)-2-(acetamidomethylene)succinate (E-2AMS) to E-2AMS hydrolase is crucial for biological function of the enzyme and the last step reaction of vitamin B(6) biological degradation. In the present study, several molecular simulation methods, including molecular docking, conventional mo...

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Detalles Bibliográficos
Autores principales: Zhang, Ji-Long, Zheng, Qing-Chuan, Li, Zheng-Qiang, Zhang, Hong-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538738/
https://www.ncbi.nlm.nih.gov/pubmed/23308285
http://dx.doi.org/10.1371/journal.pone.0053811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538738/
https://www.ncbi.nlm.nih.gov/pubmed/23308285
http://dx.doi.org/10.1371/journal.pone.0053811

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