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How Does (E)-2-(Acetamidomethylene)succinate Bind to Its Hydrolase? From the Binding Process to the Final Result
The binding of (E)-2-(acetamidomethylene)succinate (E-2AMS) to E-2AMS hydrolase is crucial for biological function of the enzyme and the last step reaction of vitamin B(6) biological degradation. In the present study, several molecular simulation methods, including molecular docking, conventional mo...
Autores principales: | Zhang, Ji-Long, Zheng, Qing-Chuan, Li, Zheng-Qiang, Zhang, Hong-Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538738/ https://www.ncbi.nlm.nih.gov/pubmed/23308285 http://dx.doi.org/10.1371/journal.pone.0053811 |
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