Reduced Cardiac Fructose 2,6 Bisphosphate Increases Hypertrophy and Decreases Glycolysis following Aortic Constriction

This study was designed to test whether reduced levels of cardiac fructose-2,6-bisphosphate (F-2,6-P(2)) exacerbates cardiac damage in response to pressure overload. F-2,6-P(2) is a positive regulator of the glycolytic enzyme phosphofructokinase. Normal and Mb transgenic mice were subject to transve...

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Detalles Bibliográficos
Autores principales: Wang, Jianxun, Xu, Jianxiang, Wang, Qianwen, Brainard, Robert E., Watson, Lewis J., Jones, Steven P., Epstein, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538739/
https://www.ncbi.nlm.nih.gov/pubmed/23308291
http://dx.doi.org/10.1371/journal.pone.0053951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538739/
https://www.ncbi.nlm.nih.gov/pubmed/23308291
http://dx.doi.org/10.1371/journal.pone.0053951

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