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Reduced Cardiac Fructose 2,6 Bisphosphate Increases Hypertrophy and Decreases Glycolysis following Aortic Constriction
This study was designed to test whether reduced levels of cardiac fructose-2,6-bisphosphate (F-2,6-P(2)) exacerbates cardiac damage in response to pressure overload. F-2,6-P(2) is a positive regulator of the glycolytic enzyme phosphofructokinase. Normal and Mb transgenic mice were subject to transve...
Autores principales: | Wang, Jianxun, Xu, Jianxiang, Wang, Qianwen, Brainard, Robert E., Watson, Lewis J., Jones, Steven P., Epstein, Paul N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538739/ https://www.ncbi.nlm.nih.gov/pubmed/23308291 http://dx.doi.org/10.1371/journal.pone.0053951 |
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