LCMV Glycosylation Modulates Viral Fitness and Cell Tropism

The glycoprotein (GP) of arenaviruses is glycosylated at 11 conserved N-glycosylation sites. We constructed recombinant lymphocytic choriomeningitis virus (rLCMV) featuring either additions or deletions of these N-glycans to investigate their role in the viral life cycle. N-glycosylation at two site...

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Detalles Bibliográficos
Autores principales: Bonhomme, Cyrille J., Knopp, Kristeene A., Bederka, Lydia H., Angelini, Megan M., Buchmeier, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538765/
https://www.ncbi.nlm.nih.gov/pubmed/23308183
http://dx.doi.org/10.1371/journal.pone.0053273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538765/
https://www.ncbi.nlm.nih.gov/pubmed/23308183
http://dx.doi.org/10.1371/journal.pone.0053273

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