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Prediction and Analysis of Antibody Amyloidogenesis from Sequences

Antibody amyloidogenesis is the aggregation of soluble proteins into amyloid fibrils that is one of major causes of the failures of humanized antibodies. The prediction and prevention of antibody amyloidogenesis are helpful for restoring and enhancing therapeutic effects. Due to a large number of po...

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Detalles Bibliográficos
Autores principales: Liaw, Chyn, Tung, Chun-Wei, Ho, Shinn-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538782/
https://www.ncbi.nlm.nih.gov/pubmed/23308169
http://dx.doi.org/10.1371/journal.pone.0053235