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Prediction and Analysis of Antibody Amyloidogenesis from Sequences
Antibody amyloidogenesis is the aggregation of soluble proteins into amyloid fibrils that is one of major causes of the failures of humanized antibodies. The prediction and prevention of antibody amyloidogenesis are helpful for restoring and enhancing therapeutic effects. Due to a large number of po...
Autores principales: | Liaw, Chyn, Tung, Chun-Wei, Ho, Shinn-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538782/ https://www.ncbi.nlm.nih.gov/pubmed/23308169 http://dx.doi.org/10.1371/journal.pone.0053235 |
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