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The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains

Nuclear factor erythroid 2-related factor 2 (Nrf2, NM 006164, 605 AA) is essential for the antioxidant responsive element (ARE)-mediated expression of a group of detoxifying antioxidant genes that detoxify carcinogens and protect against oxidative stress. Several proteins have been identified as Nrf...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Hwan, Yu, Siwang, Chen, J. Don, Kong, A.-N. Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538952/
https://www.ncbi.nlm.nih.gov/pubmed/22370642
http://dx.doi.org/10.1038/onc.2012.59