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Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells

Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors. However, studies of direct link between estrogen (especially estradiol E(2)), m...

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Detalles Bibliográficos
Autores principales: He, Yu-qi, Sheng, Jian-qiu, Ling, Xian-long, Fu, Lei, Jin, Peng, Yen, Lawrence, Rao, Jianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538979/
https://www.ncbi.nlm.nih.gov/pubmed/23143558
http://dx.doi.org/10.3858/emm.2012.44.12.079