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Activation of the Renal PI3K/Akt/mTOR Signaling Pathway in a DOCA-Salt Model of Hypertension

The present study investigated the changes that occurred in the mammalian target of rapamycin (mTOR) signaling pathway in the kidney as a result of deoxycorticosterone acetate (DOCA)-salt hypertension. Rats were implanted with DOCA strips (200 mg/kg) 1 week after unilateral nephrectomy and were then...

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Detalles Bibliográficos
Autores principales: Ma, Seong Kwon, Choi, Joon Seok, Joo, Soo Yeon, Kim, Ha Yeon, Kim, Chang Seong, Bae, Eun Hui, Lee, Jong Un, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chonnam National University Medical School 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539094/
https://www.ncbi.nlm.nih.gov/pubmed/23323219
http://dx.doi.org/10.4068/cmj.2012.48.3.150