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ATP release and purinergic signaling in NLRP3 inflammasome activation

The NLRP3 inflammasome is a protein complex involved in IL-1β and IL-18 processing that senses pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). One step- or two step-models have been proposed to explain the tight regulation of IL-1β production during inflammation. Moreover, cell...

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Detalles Bibliográficos
Autores principales: Gombault, Aurélie, Baron, Ludivine, Couillin, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539150/
https://www.ncbi.nlm.nih.gov/pubmed/23316199
http://dx.doi.org/10.3389/fimmu.2012.00414