Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers

In mammalian development, epigenetic modifications, including DNA methylation patterns, play a crucial role in defining cell fate but also represent epigenetic barriers that restrict developmental potential. At two points in the life cycle, DNA methylation marks are reprogrammed on a global scale, c...

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Detalles Bibliográficos
Autores principales: Seisenberger, Stefanie, Peat, Julian R., Hore, Timothy A., Santos, Fátima, Dean, Wendy, Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Part II: Molecular mechanisms working in the mammalian life cycle
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539359/
https://www.ncbi.nlm.nih.gov/pubmed/23166394
http://dx.doi.org/10.1098/rstb.2011.0330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539359/
https://www.ncbi.nlm.nih.gov/pubmed/23166394
http://dx.doi.org/10.1098/rstb.2011.0330

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