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Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging

The overall objectives of this research are to (i) develop azulene-based positron emission tomography (PET) probes and (ii) image COX2 as a potential biomarker of breast cancer. Several lines of research have demonstrated that COX2 is overexpressed in breast cancer and that its presence correlates w...

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Detalles Bibliográficos
Autores principales: Nolting, Donald D., Nickels, Michael, Tantawy, Mohammed N., Yu, James Y. H., Xie, Jingping, Peterson, Todd E., Crews, Brenda C., Marnett, Larry, Gore, John C., Pham, Wellington
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539664/
https://www.ncbi.nlm.nih.gov/pubmed/23316477
http://dx.doi.org/10.3389/fonc.2012.00207