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Convergent synthesis and evaluation of (18)F-labeled azulenic COX2 probes for cancer imaging
The overall objectives of this research are to (i) develop azulene-based positron emission tomography (PET) probes and (ii) image COX2 as a potential biomarker of breast cancer. Several lines of research have demonstrated that COX2 is overexpressed in breast cancer and that its presence correlates w...
Autores principales: | Nolting, Donald D., Nickels, Michael, Tantawy, Mohammed N., Yu, James Y. H., Xie, Jingping, Peterson, Todd E., Crews, Brenda C., Marnett, Larry, Gore, John C., Pham, Wellington |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539664/ https://www.ncbi.nlm.nih.gov/pubmed/23316477 http://dx.doi.org/10.3389/fonc.2012.00207 |
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