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The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery

Bacterial infections are increasingly difficult to treat owing to the spread of antibiotic resistance. A major concern is Gram-negative bacteria, for which the discovery of new antimicrobial drugs has been particularly scarce. In an effort to accelerate early steps in drug discovery, the EU-funded A...

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Detalles Bibliográficos
Autores principales: Moynie, Lucille, Schnell, Robert, McMahon, Stephen A., Sandalova, Tatyana, Boulkerou, Wassila Abdelli, Schmidberger, Jason W., Alphey, Magnus, Cukier, Cyprian, Duthie, Fraser, Kopec, Jolanta, Liu, Huanting, Jacewicz, Agata, Hunter, William N., Naismith, James H., Schneider, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539698/
https://www.ncbi.nlm.nih.gov/pubmed/23295481
http://dx.doi.org/10.1107/S1744309112044739