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The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery
Bacterial infections are increasingly difficult to treat owing to the spread of antibiotic resistance. A major concern is Gram-negative bacteria, for which the discovery of new antimicrobial drugs has been particularly scarce. In an effort to accelerate early steps in drug discovery, the EU-funded A...
Autores principales: | Moynie, Lucille, Schnell, Robert, McMahon, Stephen A., Sandalova, Tatyana, Boulkerou, Wassila Abdelli, Schmidberger, Jason W., Alphey, Magnus, Cukier, Cyprian, Duthie, Fraser, Kopec, Jolanta, Liu, Huanting, Jacewicz, Agata, Hunter, William N., Naismith, James H., Schneider, Gunter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539698/ https://www.ncbi.nlm.nih.gov/pubmed/23295481 http://dx.doi.org/10.1107/S1744309112044739 |
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