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A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells
Human mesenchymal stromal cells (hMSCs) represent an attractive cell source for clinic applications. Besides being multi-potent, recent clinical trials suggest that they secrete both trophic and immunomodulatory factors, allowing allogenic MSCs to be used in a wider variety of clinical situations. T...
Autores principales: | Alves, Hugo, Munoz-Najar, Ursula, De Wit, Jan, Renard, Auke J S, Hoeijmakers, Jan H J, Sedivy, John M, Van Blitterswijk, Clemens, De Boer, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539748/ https://www.ncbi.nlm.nih.gov/pubmed/19818093 http://dx.doi.org/10.1111/j.1582-4934.2009.00931.x |
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