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Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha

BACKGROUND: Currently, the two most commonly used fibrinolytic agents in thrombolytic therapy are recombinant tissue plasminogen activator (rt-PA) and streptokinase (SK). Whereas SK has the advantage of substantially lower costs when compared to other agents, it is less effective than either rt-PA o...

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Detalles Bibliográficos
Autores principales: Moussa, Manal, Ibrahim, Mahmoud, El Ghazaly, Maria, Rohde, Jan, Gnoth, Stefan, Anton, Andreas, Kensy, Frank, Mueller, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539880/
https://www.ncbi.nlm.nih.gov/pubmed/23253823
http://dx.doi.org/10.1186/1472-6750-12-96