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Development of a new method for identification and quantification in cerebrospinal fluid of malignant cells from breast carcinoma leptomeningeal metastasis

BACKGROUND: The diagnosis of leptomeningeal metastasis (LM) in patients with solid tumors remains difficult. The usual diagnostic methods of cytomorphological assessment of cerebro-spinal fluid (CSF) and gadolinium enhanced MRI of the entire neuraxis lack both specificity and sensitivity. The Veride...

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Detalles Bibliográficos
Autores principales: Le Rhun, Emilie, Massin, Frédéric, Tu, Qian, Bonneterre, Jacques, Bittencourt, Marcelo De Carvalho, Faure, Gilbert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539901/
https://www.ncbi.nlm.nih.gov/pubmed/23145812
http://dx.doi.org/10.1186/1472-6890-12-21