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Epithelial-Mesenchymal Transition Markers and HER3 Expression Are Predictors of Elisidepsin Treatment Response in Breast and Pancreatic Cancer Cell Lines

Elisidepsin (elisidepsin trifluoroacetate, Irvalec®, PM02734) is a new synthetic depsipeptide, a result of the PharmaMar Development Program that seeks synthetic products of marine origin-derived compounds. Elisidepsin is a drug with antiproliferative activity in a wide range of tumors. In the prese...

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Detalles Bibliográficos
Autores principales: Teixidó, Cristina, Marés, Rosó, Aracil, Miguel, Ramón y Cajal, Santiago, Hernández-Losa, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539985/
https://www.ncbi.nlm.nih.gov/pubmed/23320098
http://dx.doi.org/10.1371/journal.pone.0053645