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Construction and Characterization of an in-vivo Linear Covalently Closed DNA Vector Production System
BACKGROUND: While safer than their viral counterparts, conventional non-viral gene delivery DNA vectors offer a limited safety profile. They often result in the delivery of unwanted prokaryotic sequences, antibiotic resistance genes, and the bacterial origins of replication to the target, which may...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540006/ https://www.ncbi.nlm.nih.gov/pubmed/23216697 http://dx.doi.org/10.1186/1475-2859-11-154 |